In addition to classical toxicological in vitro assays, we also can test new substances for drug development in human tissue-specific 2D and 3D cell culture models on a cellular level. In this setting, very sensitive test methods enable us to register and document minimal alterations of cellular processes under in vivo-like conditions.
By this, the pharmaceutical industry in advance can obtain preliminary information on tolerability of a substance.
We offer Cytotoxicity assay for active substances in conventional monolayer (2D) as well as in human tissue-specific 3D cell culture models. If more precise results are required, we offer 3D reconstructions of serial slides to measure the size and volume of affected tissue areas. Thus we can provide high-quality data for the comparison of treated and untreated tissue. Further we perform molecular and cellular biological studies on morphology, proliferation, differentiation, inflammation and apoptosis.
