Automated medium for high throughput analyses

Once considered an overly difficult and complicated assay, ISH is now seeing renewed interest as an automated medium for high throughput analyses, notably through the development of new techniques. Recently we established the RNAScope® technology, which has become known for very specific results and is mainly characterised by assay robustness and high sensitivity.

PPIB (human skin, ISH, RNAScope®)

Besides providing services on the RNA level tailored to your specific needs in R&D projects, we are also able to perform Fluorescence In Situ Hybridisation (FISH) for clinical studies and diagnostic purposes on the DNA level, mainly in the diagnoses of skin cancer. We just established a melanoma – multicolour FISH, performed with a panel of four probes, which are used as markers for chromosomal aberrations, typically occurring in this disease pattern. This ancillary diagnostic instrument can help you to distinguish benign nevi from malignant melanomas in daily practice.

6p11.1-q11 CEP6 (human skin, melanoma – multicolour FISH)

6q23 MYB (human skin, melanoma-multicolour FISH)